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Ask the Doctor

About Monoclonal Antibodies

February 17, 2021 by Suzanne Broullon

Bonjour, I have received many questions regarding monoclonal antibodies, and Mountainside’s ability to provide this life-saving treatment at the hospital.

As COVID-19 cases continue to rise across the United States, investigational treatment to help lessen the effects of the virus continues to be sought after. One of those treatments is the use of monoclonal antibodies, also referred to as mAbs. The use of mAbs has received Emergency Use Authorization (EUA) by the United States Food and Drug Administration (FDA).

The use of mAbs is still considered to be in an investigational state, but the results thus far are promising. This treatment shows promise for adults who are considered to be at high risk of hospitalization if they are infected with COVID-19.

What are monoclonal antibodies?

Monoclonal antibodies are laboratory-produced molecules that mimic the immune system’s ability to respond to an illness. There are currently two different monoclonal antibodies available at Mountainside Medical Center: Bamblanivimab which is designed to block the virus from attaching to human cells to prevent further infection; and Casirivimab + Imdevimab, which neutralize and bind to receptors on the virus to decrease its ability to cause further infection.

If I tested positive for COVID-19, do I need this treatment?

To receive this treatment, you must first have a positive COID-19 test and be at high risk for progressing to severe COVID-19 illness or hospitalization. This includes those with a BMI greater than 35; individuals with certain chronic conditions or are immunosuppressed; individuals 65 years or older; those who are 55 years or older with certain chronic conditions, and those 12 to 17 years with high BMI or certain chronic medical conditions. If you feel you may be a candidate for treatment, I advise you to speak with your primary care physician to make the decision that is best for you.

How is Mountainside providing the drug?

The hospital is accepting referrals from community providers to administer monoclonal antibody therapy to qualified candidates. If you need a primary care provider to speak to visit www.mountainsidehosp.com/virtualcare and schedule a virtual care appointment with a Mountainside Medical Group physician for more information.

Thank you for the opportunity to answer your questions. I invite you to continue sending questions regarding your health interests here.

Thank you, and stay well, Valérie Allusson, M.D.

Filed Under: Ask the Doctor

Answers to Your Questions About COVID19 Vaccinations

January 20, 2021 by Suzanne Broullon

Bonjour,

I am Valérie Allusson, Chief Medical Officer at Mountainside Medical Center and a member of the Board of Directors here at the YMCA of Montclair. Thank you to everyone who submitted questions on our “Ask the Doctor” portal. Today, I am answering questions from our community about COVID-19 vaccine contraindications, or conditions where one should not receive the vaccine due to risk of harm

1. I had Guillain-Barre I believe as a result of taking the swine flu shot many years ago. I am extremely afraid any other flu shot might cause a similar reaction and therefore have not taken any shots since then. What is your opinion, please, on my possibly taking the Covid vaccine in light of this information?

I understand your concern as Guillain-Barre syndrome (GBS) can be very scary and debilitating. To date, no cases of Guillain-Barre syndrome (GBS) have been reported following vaccination among participants in the mRNA COVID-19 vaccine clinical trials (Pfizer and Moderna trials). I advise you to speak to your primary care physician to make the decision that is best for you.

It is known that there is a low or negligible risk of re-developing GSB after a flu shot. While there is a small risk of GBS associated with influenza vaccination, if you have had GBS, carefully discuss the pros and cons of the flu vaccine with your doctor.

2. Should babies be vaccinated?

The COVID-19 vaccines have only be tested on non-pregnant adults. At this time it is not recommended to vaccinate any children under 16 years of age. We will need to wait for separate clinical trials studying children’s responses to the vaccines. In addition, adults are at a much higher risk of developing severe COVID-19 illness than children.

3. I have an allergy to the flu vaccine. I was wondering if I can get the Covid vaccine? It is not a contra-indication to receive COVID 19 vaccine. It is however a precaution and you should speak to your primary care physician. Your physician will counsel you about the potential risks of developing a severe allergic reaction and balance these risks against the benefits of vaccination. Deferral of vaccination and/or consultation with an allergist-immunologist may be considered.

CDC considers a history of the following to be a contraindication to vaccination with both the Pfizer-BioNTech and Moderna COVID-19 vaccines:

  • Severe allergic reaction (e.g., anaphylaxis) after a previous dose of an mRNA COVID-19 vaccine or any of its components
  • Immediate allergic reaction of any severity to a previous dose of an mRNA COVID-19 vaccine or any of its components (including polyethylene glycol [PEG])
  • Immediate allergic reaction of any severity to polysorbate (due to potential cross-reactive hypersensitivity with the vaccine ingredient PEG)

I invite you to continue sending questions regarding health your interest here. I look forward to answering your questions.

Thank you and stay well,

Valérie Allusson, M.D.

Filed Under: Ask the Doctor

COVID19 Vaccination

December 7, 2020 by Suzanne Broullon

Bonjour,

I am Valérie Allusson, Chief Medical Officer at Mountainside Medical Center and a member of the Board of Directors here at the YMCA of Montclair. I am excited to announce that the Y and I, along with my colleagues at the hospital, have collaborated to bring you Ask the Doctor, a monthly column providing you with health information.

Today, I will be answering questions on COVID-19 vaccination.

COVID-19 Vaccination:

How effective and safe is the COVID-19 Vaccine?

Pfizer and Moderna have developed a vaccine that is administered in two doses. Both companies show that after the second dose, the vaccine is 95% effective, with no significant side effects. The vaccines have the ability to prevent COVID-19, but also prevent severe cases of COVID-19.

When will the vaccines be available?

Both Pfizer and Moderna have applied for an Emergency Use Authorization (EUA) with the Food and Drug Administration (FDA). After approval from the FDA, the CDC will provide a framework on which groups to prioritize. The first groups who will receive the vaccines will be nursing home residents and healthcare workers. It is expected that vaccines will be made available to this priority group, including the Mountainside Medical Center, before month’s end.

Will people still need to wear a mask, social distance, and wash hands after being vaccinated?

Yes. It is recommended you continue wearing a mask, social/physical distancing, and washing your hands until the general population is vaccinated.

I invite you to send your questions regarding health topics of your interest here. I look forward to answering your questions.

Thank you and stay well,

Valérie Allusson, M.D.

Filed Under: Ask the Doctor

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Since 1891, the YMCA of Montclair works to empower young people, improve health and well-being, and inspire action in and across our community.
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