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About Monoclonal Antibodies

February 17, 2021 by Suzanne Broullon

Bonjour, I have received many questions regarding monoclonal antibodies, and Mountainside’s ability to provide this life-saving treatment at the hospital.

As COVID-19 cases continue to rise across the United States, investigational treatment to help lessen the effects of the virus continues to be sought after. One of those treatments is the use of monoclonal antibodies, also referred to as mAbs. The use of mAbs has received Emergency Use Authorization (EUA) by the United States Food and Drug Administration (FDA).

The use of mAbs is still considered to be in an investigational state, but the results thus far are promising. This treatment shows promise for adults who are considered to be at high risk of hospitalization if they are infected with COVID-19.

What are monoclonal antibodies?

Monoclonal antibodies are laboratory-produced molecules that mimic the immune system’s ability to respond to an illness. There are currently two different monoclonal antibodies available at Mountainside Medical Center: Bamblanivimab which is designed to block the virus from attaching to human cells to prevent further infection; and Casirivimab + Imdevimab, which neutralize and bind to receptors on the virus to decrease its ability to cause further infection.

If I tested positive for COVID-19, do I need this treatment?

To receive this treatment, you must first have a positive COID-19 test and be at high risk for progressing to severe COVID-19 illness or hospitalization. This includes those with a BMI greater than 35; individuals with certain chronic conditions or are immunosuppressed; individuals 65 years or older; those who are 55 years or older with certain chronic conditions, and those 12 to 17 years with high BMI or certain chronic medical conditions. If you feel you may be a candidate for treatment, I advise you to speak with your primary care physician to make the decision that is best for you.

How is Mountainside providing the drug?

The hospital is accepting referrals from community providers to administer monoclonal antibody therapy to qualified candidates. If you need a primary care provider to speak to visit www.mountainsidehosp.com/virtualcare and schedule a virtual care appointment with a Mountainside Medical Group physician for more information.

Thank you for the opportunity to answer your questions. I invite you to continue sending questions regarding your health interests here.

Thank you, and stay well, Valérie Allusson, M.D.

Filed Under: Ask the Doctor

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Park Street YMCA
973-744-3400
25 Park Street, Montclair, NJ 07042
Geyer Family YMCA
973-783-7640
159 Glenridge Ave. Montclair, NJ 07042
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Since 1891, the YMCA of Montclair works to empower young people, improve health and well-being, and inspire action in and across our community.
Serving Bloomfield, Bloomingdale, Clifton, Cedar Grove, Glen Ridge, Haskell, Montclair, Verona, and West Milford.